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軸索反射反應(yīng)
當對精確界定的皮膚表面給予熱（如用moor SHO2進行加熱）、電或化學（如用moor MIC2離子導(dǎo)入乙酰膽堿）刺激時，除受刺激區(qū)域的皮膚以外，其周邊區(qū)域皮膚的微循環(huán)血流也出現(xiàn)上升，形成潮紅、充血、甚至水腫等反應(yīng)。這種由刺激引發(fā)逆向神經(jīng)信號傳輸，導(dǎo)致神經(jīng)支配的血管發(fā)生舒張的過程即軸突反射性炎癥反應(yīng)，也稱為充血反應(yīng)。軸突反射性炎癥反應(yīng)的缺失常常意味著周圍神經(jīng)特別是小纖維神經(jīng)功能異常，是對由糖尿病或其它疾病引發(fā)的小纖維神經(jīng)病或周圍神經(jīng)疾病的靈敏檢測指標，可對糖尿病足等疾病做出準確的早期診斷。
激光多普勒血流監(jiān)測儀（moorVMS-LDF）用于評價血管舒張的幅度以及其隨時間的變化，而通過激光多普勒成像儀（moorLDI2）或激光散斑成像儀（moorFLPI）可得到充血面積等更多的信息。例如在糖尿病足早期，下肢小纖維神經(jīng)功能受損導(dǎo)致其充血面積明顯小于正常反應(yīng)。
軸索反射試驗
軸索反射試驗過程
所需設(shè)備
moorLDI2點掃描激光多普勒成像
moorVMS-HEAT溫度控制模塊
moorFLPI-2激光散斑血流成像
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